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Material Safety Data Sheet

Product No. 18706 DAPI, Fluorescent Dye                                                       

Issue Date (02-04-06)

Review Date (03-14-07)

Section 1: Product and Company Identification

Product Name: DAPI, Fluorescent Dye

Synonym: 4’, 6-Diamidino-2-Phenylindole Dihydrochloride, 2-(4-Amidinophenyl)-6-indolecarbamidine dihydrochloride

Company Name

Ted Pella, Inc. and PELCO International, P.O. Box 492477, Redding, CA 96049-2477
Domestic Phone  (800) 237-3526 (Mon-Thu. 6:00AM to 4:30PM PST; Fri 6:00AM to 4:00PM PST)

International Phone (01) (530) 243-2200 (Mon-Thu. 6:00AM to 4:30PM PST; Fri 6:00AM to 4:00PM PST)

Chemtrec Emergency Number 1-800-424-9300 24 hrs a day.

Section 2: Composition / Information on Ingredients

Principle Hazardous Component(s)
(chemical and common name(s)) (Cas. No)

%

OSHA
PEL

mg/m3

ACGIH 
TLV mg/m3

NTP

IARC

OSHA
regulated

4’, 6-Diamidino-2-Phenylindole Dihydrochloride

 (28718-90-3)

99

ND

ND

No

No

No

Acetone (67-64-1)

1

ND

ND

No

No

No

*

None

 

 

 

 

 

* The following substance(s) may be present as residual components of production.

Section 3: Hazard Identification
Emergency overview

Appearance: Solid, Yellow powder.

Immediate effects: Irritation.

Potential health effects

Primary Routes of entry: Inhalation, ingestion, eye and skin.

Target Organs: Liver and kidneys.
Signs and Symptoms of Overexposure: To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.

Eyes: Causes eye irritation.

Skin: May be harmful if absorbed through the skin. Causes sensitization; dermatitis.

Ingestion: May be harmful if swallowed.

Inhalation: May be harmful if inhaled. Material is irritating to mucous membranes and upper respiratory tract.

Chronic Exposure: Chemical Listed As Carcinogen Or Potential Carcinogen: No

See Toxicological Information (Section11)

Potential environmental effects

See Ecological Information (Section 12)

Section 4: First Aid Measures
If accidental overexposure is suspected

Eye(s) Contact: Immediately flush eyes with copious amounts of water for at least 15 minutes.

Skin Contact: Immediately wash skin with soap and copious amounts of water.
Inhalation: Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Ingestion: If person is conscious, wash out with water. Call a physician.

Note to physician

Treatment: ND

Medical Conditions generally Aggravated by Exposure: ND

Section 5: Fire Fighting Measures
Flash Point: NIF
Flammable Limits: NIF

Auto-ignition point: NIF
Fire Extinguishing Media: Water spray, carbon dioxide, dry chemical powder, or appropriate foams.
Special Fire Fighting Procedures: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Unusual Fire and Explosion Hazards: ND.

Hazardous combustion products: Emits toxic fumes under fire conditions.

DOT Class: Not regulated

Section 6: Accidental Release Measures
Steps to be Taken in Case Material is Released or Spilled: Wear respirator, chemical safety goggles, rubber boots, and heavy rubber gloves. Avoid raising dust. Sweep up, place in a bag and hold for waste disposal. Ventilate area and wash spill site after material pickup is complete.
Waste Disposal Methods: Dispose of waste according to Federal, State and Local Regulations.

Section 7: Handling and Storage
Precautions to be Taken in Handling and Storage: Do not breathe dust. Avoid contact with eyes, skin, and clothing. Avoid prolonged or repeated exposure. Keep tightly closed and avoid light.

Storage temperature: -20° C

Storage Pressure: ND

Section 8: Exposure Controls / Personal Protection
Engineering Controls

Ventilation required: Local mechanical exhaust required.

Personal Protection Equipment

Respiratory protection: Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a dusk mask type N95 (US) or type P1 (EN 143) respirator.

Protective gloves: Compatible chemical-resistant gloves.
Skin protection: Wear protective clothing.
Eye protection: Wear chemical safety goggles.
Additional clothing and/or equipment: Eye bath and safety shower.

Exposure Guidelines

See Composition/Information on Ingredients (Section2)

Section 9 Physical and Chemical Properties
Appearance and Physical State: Solid, Yellow powder.

Odor (threshold): ND

Specific Gravity (H2O=1): ND

Vapor Pressure (mm Hg): ND

Vapor Density (air=1): ND

Percent Volatile by volume: ND

Evaporation Rate (butyl acetate=1): ND

Boiling Point: ND

Freezing point / melting point: ND
pH: ND
Solubility in Water: Soluble
Molecular Weight: 350.25

Formula: C16H15N5·2H2O

Section 10: Stability and Reactivity
Stability: Stable
Conditions to Avoid: ND

Materials to Avoid (Incompatibility): Strong oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide, Nitrogen oxides, and Hydrogen chloride gas.
Hazardous Polymerization: Will not occur.

Section 11: Toxicological Information

Results of component toxicity test performed: ND

Human experience: ND

This product does not contain any compounds listed by NTP or IARC or regulated by OSHA as a carcinogen.

Section 12: Ecological Information

Ecological Information: NIF

Chemical Fate Information: NIF

Section 13 Disposal Considerations

RCRA 40 CFR 261 Classification: Contact a licensed professional waste disposal service to dispose of this material.

Federal, State and local laws governing disposal of materials can differ. Ensure proper disposal compliance with proper authorities before disposal.

Section 14: Transportation Information

US DOT Information: Proper shipping name: Not regulated

IATA: Proper shipping name: Not regulated

IMO: Proper shipping name: Not regulated

Marine Pollutant: No

Canadian TDG: ND

IMDG Page: ND

Limitations: ND

Section 15: Regulatory Information

United States Federal Regulations

MSDS complies with OSHA’s Hazard Communication Rule 29, CFR 1910.1200.

SARA: Listed in category 313.

SARA Title III: This product is or contains a component that is subject to SARA 313 reporting requirements.

RCRA: ND

TSCA: ND

CERCLA: ND

State Regulations

California Proposition 65: ND

International Regulations

Canada WHMIS: This product has been classified in accordance with hazard criteria of the CPR, and the MSDS contains all the information required by the CPR. DSL: No. NDSL: No.

Europe EINECS Numbers: 4’,6-Diamidino-2-Phenylindole Dihydrochloride (28718-90-3) EINECS #: 249-186-7. 

Section 16: Other Information

Label Information: Irritant.

European Risk and Safety Phrases: R 36/37/38: Risk Phrases: Irritating to eyes, respiratory system and skin. S 26-36: Safety Phrases: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing.  

European symbols needed: Xi.

Canadian WHMIS Symbols: ND

HMIS® Hazard Rating: Health: 2*; Flammability: 0; Physical Hazard: 0

*additional chronic hazards present, see section 2

NFPA Hazard Rating: Health: 2; Fire: 0; Reactivity: 0
(0=least, 1=Slight, 2=Moderate, 3=High, 4=Extreme)

Abbreviations used in this document

NE= Not established

NA= Not applicable

NIF= No Information Found

ND= No Data

Disclaimer
Ted Pella, Inc. makes no warranty of any kind regarding the information furnished herein. Users should independently determine the suitability and completeness of information from all sources. While this data is presented in good faith and believed to be accurate, it should be considered only as a supplement to other information gathered by the user. It is the User's responsibility to assure the proper use and disposal of these materials as well as the safety and health of all personnel who may work with or otherwise come in contact with these materials.

 

MSDS Form 0013F1 V2